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Corneal Collagen Crosslinking with Riboflavin (C3-RŪ),is
being used to treat keratoconus and ectasias of the
cornea.It has proven to strengthen the weak corneal
structure. This method works by increasing collagen
crosslinking, which are the natural "anchors" within the
cornea. These anchors are responsible for preventing the
cornea from bulging out and becoming steep and irregular,
consequence of advanced keratoconus.
Keratoconus is a disease of the cornea that makes the cornea
become weak and may gradually bulge outward. Most often,
this bulging is in the lower half of the cornea and first
presents as astigmatism, however not all astigmatism is due
to keratoconus. In mild or early stages of keratoconus (forme
fruste keratoconus), eyeglasses may correct the astigmatic
vision.
The 30-minute corneal crosslinking treatment is performed in
the doctor's office. During the treatment, custom-made
riboflavin eye drops are applied to the cornea, which is
then activated by ultraviolet light. This amazingly simple
process has been shown in laboratory and clinical studies to
increase the amount of collagen cross-linking in the cornea
and strengthen the cornea. In published European studies,
such treatments were proven safe and effective in patients.
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